MilestonesBrief History of Our Company

1994

The company was founded under the name Dr. Franz Tatzber KEG, reagents and recycling. The target of the foundation was development and production of diagnostic procedures in close cooperation with Austrian scientific Institutions.

2006

From 2006-2011 it was the only SME contributing to COST B35 action. Additionally, a number of sales representations were acquired for trading in Austria.

The company has developed into a successful and innovative diagnostic method manufacturer in the past decade and has developed a still increasing number of diagnostics. Moreover, it is a member of several scientific societies and also holds some patents.

Our TeamWho we are

Wonisch Willibald 036R

Priv. Doz. (PD) Mag. Dr. Willibald Wonisch

Address:

Donaustrasse 137
A-3421 Höflein/D.

Phone:                      ++43-650-52-99-540

Fax:                            ++43-2243-80022

Mail:                           office@omnignostica.com

Employment history:

Chief Scientific Officer and Product Manager – since 1994

Chief executive officer – since 2016

EU-Projects:

  1. 2000-2004 VITAGE
  2. 2006-2010 COST-B35
  3. 2010-2015   BIOCLAIMS

Scientific Publications:

Reference List:

show references

  1. Wonisch Willibald, Schaur R. Jörg, Bilinski Tomek, Esterbauer Hermann (1995) Assessment of growth inhibition by aldehydic lipid peroxidation products and related aldehydes by Saccharomyces cerevisiae. Cell Biochem. Funct. 13(2):91-98
  2. Wonisch Willibald, Tatzber Franz, Schaur R. Jörg, Zarkovic Neven, Guttenberger Helmut, Esterbauer Hermann (1997) Cell cycle inhibition by the lipid peroxidation product 4-hydroxynonenal in the yeast Saccharomyces cerevisiae. Naunyn-Schmiedebergs Archives of Pharmacology 356(4):pp 72-72 (Meeting Abstract)
  3. Tatzber Franz, Wonisch Willibald, Schmidl Elisabeth, Esterbauer Hermann (1997) Quantitative determination of oLAb titers in various animal species. Biofactors 6(2):125-30
  4. Wonisch Willibald, Hayn Marianne, Schaur R. Jörg, Tatzber Franz, Kranner Ilse, Grill Dieter, Winkler Rudolf, Bilinski Tomek, Kohlwein Sepp D., Esterbauer Hermann (1997) Increased stress parameter synthesis in the yeast Saccharomyces cerevisiae after treatment with 4-hydroxy-2-nonenal. FEBS Lett. 405(1):11-15
  5. Wonisch Willibald, Kohlwein Sepp D., Schaur R. Jörg, Tatzber Franz, Guttenberger Helmut, Zarkovic Neven, Winkler Rudolf, Esterbauer Hermann (1998) Treatment of the budding yeast Saccharomyces cerevisiae with the lipid peroxidation product 4-HNE provokes a temporary cell cycle arrest in G1 phase. Free Radic Biol Med. 25(6):682-7
  6. Smolle Karl-Heinz, Wonisch Willibald, Tatzber Franz, Kaufmann P., Khoschsorur G., Aigner R. (1999) Continuous Hemofiltration (Cvvhf) – Effects on inflammatory parameters and lipid peroxidation products in critically Ill patients. Shock 12(1) pp 120-120 (Meeting Abstract)
  7. Winkler Rudolf, Griebenow Sirid, Wonisch Willibald (2000) Effect of iodide on total antioxidant status of human serum. Cell Biochem Funct 18(2):143-6
  8. Meraji S., Abuja Peter M.; Hayn Marianne, Kostner G.M., Morris R., Oraii S., Tatzber Franz, Wonisch Willibald, Zechner Rudolf, Gey K.F. (2000) Relationship between classic risk factors, plasma antioxidants and indicators of oxidant stress in angina pectoris (AP) in Tehran. Atherosclerosis 150(2):403-12
  9. Wonisch Willibald, Zellnig G., Kohlwein Sepp D., Schaur R. Jörg, Bilinski Tomek, Tatzber Franz, Esterbauer Hermann (2001) Ultrastructural analysis of HNE-treated Saccharomyces cerevisiae cells reveals fragmentation of the vacuole and an accumulation of lipids in the cytosol. Cell Biochem Funct 19(1):59-64
  10. Schippinger Gert, Wonisch Willibald, Abuja Peter M., Fankhauser Florian, Winklhofer-Roob Brigitte M., Halwachs Gabriele (2002) Lipid peroxidation and antioxidant status in professional American football players during competition. J. Clin. Invest. 32:686-692.
  11. Stanger Olaf, Semmlrock H.J., Wonisch Willibald, Bös Ursula, Pabst E., Wascher Thomas C. (2002) Effects of folate treatment and homocysteine – lowering on resistance vessel reactivity in atherosclerotic subjects. JPET 303:158-162.
  12. Wonisch Willibald and Schaur R. Jörg (2001) Chemistry of Glutathione; Significance of glutathione in plant adaptation to the environment, pp 13-26, Eds. D. Grill, M. Tausz, L.J. de Kok. Kluwer Academic Publishers, Dordrecht/Boston/London
  13. Tatzber Franz, Griebenow Sirid, Wonisch Willibald and Winkler Rudolf. (2003) Dual method for the determination of peroxidase activity and total peroxides – iodide leads to a significant increase of peroxidase activity in human sera. Anal. Biochem. 316:147-153.
  14. Lindschinger Meinrad, Nadlinger Karl, Adelwöhrer Norbert, Holweg Karin, Wögerbauer Markus, Birkmayer Jörg, Smolle Karl-Heinz, Wonisch Willibald. (2004) Oxidative stress: potential of distinct peroxide determination systems. Clin Chem Lab Med 42(8):907-914.
  15. Winklhofer-Roob Brigitte, Meinitzer Andreas, Maritschnegg Michaela, Roob Johannes, Khoschsorur Gholamali, Ribalta Josep, Sundl Isabella, Wuga Sandra, Wonisch Willibald, Tiran Beate, Rock Edmond fort he Vitage study group. (2004) Effects of Vitamin E Depletion/Repletion on Biomarkers of Oxidative Stress in Healthy Aging. Ann N.Y. Acad. Sci. 1031:361-364.
  16. Lindschinger Meinrad, Wonisch Willibald. (2006) POX-Act assay and d-ROMs test – what are the facts? Clin Chem Lab Med 44(1):121-122.
  17. Wonisch Willibald, Uhl Karl, Schimetta Wolfgang, Rabl Hans. (2005) Pre-operative delivery of a vitamin cocktail diminished oxidative stress after vascular surgery in PAD patients – a pilot investigation. Biofactors 24:299-303.
  18. Wurzinger Sabine, Bratu Mirela, Wonisch Willibald, Wintersteiger Reinhold, Halwachs-Baumann Gabriele, Porta Sepp (2006) Interdependency of the oxidizability of lipoproteins and peroxidase activity with base excess, HCO3, pH and magnesium in human venous and capillary blood. Life Sci 78:1754-1759.
  19. Wonisch W, Lindschinger M, Schippinger G, Smolle KH, Tatzber F, Halwachs-Baumann G. (2006) Freie Radikale, Antioxidantien, Lipidperoxidation, Labor-Diagnostik. In: Biopolyphenole und Magnesium – Südsteirische Schätze, pp 60-75, Eds. S. Porta and D. Gualtieri. Styria Printshop Druck GmbH, Graz, Austria.
  20. Cipak Ana, Hasslacher Meinhard, Tehlivets Oksana, Collinson Emma J., Zivkovic Morana, Matijevic Tanja, Wonisch Willibald, Waeg Georg, Dawes Ian W., Zarkovic Neven, Kohlwein Sepp D. (2006) Saccharomyces cerevisiae strain expressing a plant fatty acid desaturase produces polyunsaturated fatty acids and is susceptible to oxidative stress induced by lipid peroxidation. Free Radic Bio Med 40:897-906.
  21. Nikolic-Heitzler Vjeran, Rabuzin Filip, Tatzber Franz, Vrkic Nada, Bulj Nikola, Borovic Suzana, Wonisch Willibald, Sunko Branka Mazul, Zarkovic Neven (2006) Persistent oxidative stress after myocardial infarction treated by percutaneous coronary intervention. Tohoku J Exp Med 210:247-255.
  22. Schippinger G, Fankhauser F, Abuja PM, Winklhofer-Roob BM, Nadlinger K, Halwachs-Baumann G, Wonisch W. (2009) Competitive and seasonal oxidative stress in elite alpine ski racers. Scand J Med Sci. Sports 19:206-12.
  23. Smolle KH, Kaufmann P, Stadlbauer V, Tatzber F, Winklhofer-Roob BM, Aigner R, Khoschsorur G, Wonisch W. (2010) Intermittent Haemodialysis-induced oxidative stress and the effect on inflammatory parameters in critically ill patients. CEMED 4:79-88.
  24. Trinker M, Smolle KH, Scheidl S, Tatzber F, Lindschinger M, Wonisch W. (2010) Serum total peroxides are increased in patients with stage IV compared to stage IIb peripheral arterial disease: Percutaneous Transluminal Angioplasty may generate epitopes for autoantibodies against oxidized low density lipoprotein. CEMED 4:89-97.
  25. Prasetyo EN, Kudanga T, Steiner W, Murkovic M, Wonisch W, Nyanhongo GS, Guebitz GM. (2010) Cellular and plasma antioxidant activity assay using tetramethoxy azobismethylene quinone. Free Radic Biol Med 49:1205-11.
  26. Prasetyo EN, Wonisch W, Nyanhongo GS, Guebitz GM. (2012) A unique two-way approach for the validation of total antioxidant capacity of serum samples. Eur J Clin Invest 42(4):432-38.
  27. Stanger O, Wonisch W. (2012) Enzymatic and Non-enzymatic antioxidative effects of folic acid and its reduced derivates. Subcell Biochem 56:131-61.
  28. Wonisch W, Falk A, Sundl I, Winklhofer-Roob BM, Lindschinger M. (2012) Oxidative stress increases continuously with BMI and age with deteriorations in males. The Aging Male 15(3):159-65.
  29. Tripolt NJ, Leber B, Blattl D, Eder M, Wonisch W, Scharnagl H, Stojakovic T, Obermayer-Pietsch B, Wascher TC, Pieber TR, Stadlbauer V, Sourij H. (2013) Short communication: Effect of supplementation with Lactobacillus casei Shirota on insulin sensitivity, beta-cell function, and markers of endothelial function and inflammation in subjects with metabolic syndrome – a pilot study. J. Dairy Sci 96:89-95.
  30. Stoppe C, Werker T, Rossaint R, Dollo R, Lue H, Wonisch W, Menon A, Goetzenich A, Bruells CS, Coburn M, Kopp R, Bucala R, Bernhagen J, Rex S. (2013) What is the significance of perioperative release of macrophage migration inhibitory factor in cardiac surgery? Antioxidants & Redox Signaling 19(3):231- 39.
  31. Stevanovic A., Coburn M., Menon A., Rossaint R., Heyland D., Schälte G., Werker T., Wonisch W., Kiehntopf M., Goetzenich A., Rex S., Stoppe C. (2014) The Importance of Intraoperative Selenium Blood Levels on Organ Dysfunction in Patients Undergoing Off-Pump Cardiac Surgery: A Randomised Controlled Trial. PloS One 9(8):e104222.
  32. Tatzber F., Resch U., Wonisch W., Berent R., Sinzinger H. (2017) Oxidation injury and local mediator interplay in Marfan syndrome. Vasa 46(3):149-50.

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